Investigating Neoplastic Progression of Ulcerative Colitis with Label-Free Comparative Proteomics
نویسندگان
چکیده
منابع مشابه
Results of Endorectal Heal J Pouch with Ulcerative Colitis
This study evaluates the results of endorectal Ileal J Pouch Anal Anastomosis (IJPAA) in 13 patients with Ulcerative colitis and 7 patients with familial adenomatous polyposis in 6 years in Emam Hosein Hospital. In the last, for this patients permanent Ileostomy was performed, but with (IJPAA) operation permanent Ileostomy is abandoned. Two patients, total colectomy rectal mocosectomy and ilea...
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Primary sclerosing cholangitis is a cholestatic condition with unknown etiology and long-standing, progressive course, leading to cirrhosis and requiring orthotropic liver transplant. In approximately 80%, primary sclerosing cholangitis is accompanied by inflammatory bowel disease, and in most cases the recognition of bowel disease precedes the diagnosis of primary sclerosing cholangitis. We de...
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This is a preliminary report of 28 patients with ulcerative colitis who we surgically treated with "J" pouch endorectal pull-through operation from 1978 to 1996. All patients are continent with a median stool frequency of 4 times per day, no night soilage. low postoperative complications and one mortality due to pulmonary embolism.
متن کاملMicrosatellite instability in inflamed and neoplastic epithelium in ulcerative colitis.
BACKGROUND Several genetic alterations have been documented in dysplasia and cancer developing in ulcerative colitis (UC). However, the microsatellite instability (MSI) status has rarely been described, especially in the inflamed epithelium of UC. AIMS To study MSI status during neoplastic and inflammatory changes in UC. METHODS Seventy five surgically resected samples of colorectal mucosa,...
متن کاملMass Spectrometry-Based Label-Free Quantitative Proteomics
In order to study the differential protein expression in complex biological samples, strategies for rapid, highly reproducible and accurate quantification are necessary. Isotope labeling and fluorescent labeling techniques have been widely used in quantitative proteomics research. However, researchers are increasingly turning to label-free shotgun proteomics techniques for faster, cleaner, and ...
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ژورنال
عنوان ژورنال: Journal of Proteome Research
سال: 2011
ISSN: 1535-3893,1535-3907
DOI: 10.1021/pr100574p